Dr Daniel Evans
I obtained my PhD in the field of synthetic organic chemistry, preparing a model system representative of the biologically active guanine natural product cylindrospermopsin, under the guidance of Dr Patrick Murphy.
The success of this work led to a two year postdoctoral position at the school of chemistry in Bangor. This role was concerned with the development of a stereoselective total synthesis of cylindrospermopsin and the preparation of guanidine containing heterocycles for use in the synthesis of related natural products.
• Biologically active natural products
• Organic synthesis of novel compounds
• Chemical modification of natural products
• Preparative and analytical chromatographic techniques
I am a Research Officer (Synthetic Chemistry).
• Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway, D. M. Evans, P. J. Murphy, P. N. Horton, M. B. Hursthouse, RSC Adv., 2014, 4, 20744.
• Iodocyclisation reactions of Boc- and Cbz-protected N-allylguanidines, Z. Al Shuhaiba, D. H. Davies, M. Dennis, D. M. Evans, M. D. Fletcher, H. Franken, P. Hancock, J. Hollinshead, I. Jones, K. Kähm, P. J. Murphy, R. Nash, D. Potter, R. Rowles, Tetrahedron., 2014, 70, 4412.
• The cylindrospermopsin alkaloids, D. M. Evans, P. J. Murphy, The Alkaloids: Chemistry and Biology, 2011, 70, 1.
• A biomimetic approach to the cylindrospermopsin alkaloids, D. M. Evans, P. J. Murphy, Chem. Commun., 2011, 47, 3225.
• Cyclisation reactions of bis-protected guanidines, C. Albrecht, S. Barnes, H. Böckemeier, D. Davies, M. Dennis, D. M. Evans, M. D. Fletcher, I. Jones, V. Leitmann, P. J. Murphy, R. Rowles, R. Nash, R. A. Stephenson, P. N. Horton, M. B. Hursthouse, Tetrahedron Lett., 2008, 49, 185.